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GW788388
Cat. No.:
OB0225LY-0201
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR and LC-MS.
Size:
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Product Overview
Description:
GW788388 is a small molecule compound that acts primarily as a selective TGF-β signaling pathway inhibitor.
Synonym:
GW 788388; 452342-67-5; 4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide; N-(Oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzamide; 4-[4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl]-N-(tetrahydropyran-4-yl)benzamide; N-(Oxan-4-yl)-4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]benzamide
CAS No.:
452342-67-5
Compound CID:
10202642
Formula:
C25H23N5O2
Formula Weight:
425.48
Specification
Relative Density:
1.34 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GW788388 can be used to study cell proliferation, fibrosis, and the impact of the tumor microenvironment in different disease states.
Library Information
Targets:
TGF-β receptor family
Receptors:
ALK5
Pathways:
TGF-beta/Smad signaling; Angiogenesis; Stem cells
Plate Number:
AOCL-3
Plate Location:
e5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
10 mg/mL; 23.5 mM
ALogP:
2.862
HBA_Count:
5
HBD_Count:
2
Rotatable Bond:
5
