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Brivanib (alaninate)
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Cat. No.:
OB0125LY-071
Size:
1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg
CAS No.:
649735-63-7
Compound CID:
11154925
Specification
Description:
Brivanib (alaninate) is an inhibitor of both VEGF and FGF signaling pathways.
Formula Weight:
441.46
Stability:
3 years in powder form.
Applications:
Brivanib (alaninate) can be used for target discovery and drug screening.
Storage:
Storage at -20°C.
Formula:
C22H24FN5O4
Appearance:
Solid
Purity:
99.6%
Identity:
Confirmed by NMR and LC-MS.
Targets&IC50:
VEGFR2: 25 nM; FLK1: 89 nM; FGFR1: 148 nM; VEGFR1: 380 nM
Relative Density:
1.42 g/cm3
Library Information
Plate Number:
AOCL-6
Plate Location:
e9
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Angiogenesis; Autophagy; Tyrosine kinase/adaptors
Targets:
VEGFR; FGFR; Autophagy
Receptors:
Autophagy; FGFR1; Flk1; VEGFR; VEGFR1; VEGFR2
DMSO Max Solubility (mg/mL):
82 mg/mL
DMSO Max Solubility (mM):
185.7 mM
Ethanol Max Solubility (mg/mL):
82 mg/mL
Ethanol Max Solubility (mM):
185.7 mM
Saline Max Solubility (mg/mL):
9 mg/mL
Saline Max Solubility (mM):
18.37 mM
ALogP:
3.383
HBA_Count:
6
HBD_Count:
2
Rotatable Bond:
8