Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
SB-431542
Cat. No.:
OB0225LY-0189
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
SB-431542 is a small molecule compound that is primarily used to inhibit TGF-β receptor activity and affect cell signaling.
Synonym:
SB 431542; 301836-41-9; 4-(4-(Benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide; 4-[4-(1,3-Benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide; 4-(4-(1,3-Benzodioxole-5-yl)-5-(2-pyridyl)-1H-imidazole-2-yl)benzamide; Benzamide, 4-(4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl)-; 4-(5-Benzo[1,3]dioxol-5-yl-4-pyridin-2-yl-H-imidazol-2-yl)-benzamide
CAS No.:
301836-41-9
Compound CID:
4521392
Formula:
C22H16N4O3
Formula Weight:
384.39
Specification
Relative Density:
1.373 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SB-431542 can be used to study cell migration and invasion mechanisms.
Library Information
Targets:
TGF-beta/Smad; ALK family
Receptors:
ALK4; ALK5; ALK7; TGF-β receptor
Pathways:
Angiogenesis; Stem cells; Tyrosine kinase/adaptors
Plate Number:
AOCL-3
Plate Location:
d3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
16.67 mg/mL; 43.36 mM
Ethanol Max Solubility:
3.8 mg/mL; 10 mM
Solubility:
10% DMSO+90% Saline: 0.1 mg/mL (0.26 mM)
ALogP:
3.447
HBA_Count:
5
HBD_Count:
2
Rotatable Bond:
4
