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- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
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- Microbiology/Virology-Targeted Compounds
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- PI3K/Akt/mTOR-Targeted Compounds
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- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
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ZM39923 hydrochloride
Cat. No.:
OB0125LY-076
Appearance:
Solid
Purity:
98%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
ZM39923 hydrochloride is an JAK1/3 inhibitor that selectively inhibits MEK kinase in the MAPK signaling pathway.
Synonym:
1021868-92-7; JAK3 Inhibitor IV; ZM 39923 HCl; ZM 39923 hydrochloride; 3-(Benzyl (isopropyl)amino)-1-(naphthalen-2-yl)propan-1-one hydrochloride; 3-[Benzyl (propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one, hydrochloride; 1-Propanone, 3-[ (1-methylethyl) (phenylmethyl)amino]-1-(2-naphthalenyl)-, hydrochloride (1: 1); 3-[Benzyl (propan-2-yl)amino]-1-(naphthalen-2-yl)propan-1-one hydrochloride; 3-[Benzyl (propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride; 3-[ (1-Methylethyl) (phenylmethyl)amino]-1-(2-naphthalenyl)-1-propanone hydrochloride; N-Benzyl-N-isopropyl-3-(2-naphthyl)but-3-en-1-amine, HCl
CAS No.:
1021868-92-7
Compound CID:
176406
Formula:
C23H25NO·HCl
Formula Weight:
367.91
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ZM39923 hydrochloride is used as a tool compound in oncology studies to investigate the effects of MEK inhibition on cancer cell proliferation and survival.
Library Information
Targets:
EGFR; JAK
Receptors:
EGFR; JAK; JAK1; JAK3; TGM2
Pathways:
Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Tyrosine kinase/adaptors; Stem cells
Plate Number:
AOCL-18
Plate Location:
e6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
28 mg/mL; 76.1 mM
Water Max Solubility:
1 mg/mL
Ethanol Max Solubility:
8 mg/mL; 21.74 mM
ALogP:
5.424
HBA_Count:
1
HBD_Count:
0
Rotatable Bond:
7





