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ZM39923 hydrochloride
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Cat. No.:
OB0125LY-076
Size:
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
CAS No.:
1021868-92-7
Compound CID:
176406
Specification
Description:
ZM39923 hydrochloride is an JAK1/3 inhibitor that selectively inhibits MEK kinase in the MAPK signaling pathway.
Formula Weight:
367.91
Stability:
3 years in powder form.
Applications:
ZM39923 hydrochloride is used as a tool compound in oncology studies to investigate the effects of MEK inhibition on cancer cell proliferation and survival.
Storage:
Storage at -20°C.
Formula:
C23H25NO·HCl
Appearance:
Solid
Purity:
98%
Identity:
Confirmed by NMR and HPLC.
Library Information
Plate Number:
AOCL-18
Plate Location:
e6
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Tyrosine kinase/adaptors; Stem cells
Targets:
EGFR; JAK
Receptors:
EGFR; JAK; JAK1; JAK3; TGM2
DMSO Max Solubility (mg/mL):
28 mg/mL
DMSO Max Solubility (mM):
76.1 mM
Water Max Solubility (mg/mL):
1 mg/mL
Ethanol Max Solubility (mg/mL):
8 mg/mL
Ethanol Max Solubility (mM):
21.74 mM
ALogP:
5.424
HBA_Count:
1
Rotatable Bond:
7