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RepSox
Cat. No.:
OB0225LY-0187
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
RepSox is a compound with properties that inhibit the TGF-β signaling pathway.
Synonym:
ALK5 Inhibitor II; SJN 2511; E-616452; 446859-33-2; 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine; 2-[5-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine; 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
CAS No.:
446859-33-2
Compound CID:
449054
Formula:
C17H13N5
Formula Weight:
287.32
Specification
Relative Density:
1.297 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
RepSox can be used to study the role of TGF-β in cell differentiation or play an important role in stem cell reprogramming.
Library Information
Targets:
TGF-beta/Smad; ALK family
Receptors:
ALK5; TGF-β receptor; TGFβR1
Pathways:
Angiogenesis; Stem cells; Tyrosine kinase/adaptors
Plate Number:
AOCL-3
Plate Location:
c11
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
15 mg/mL; 52.21 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
3.192
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
2
