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CEP-33779
Cat. No.:
OB0125LY-077
Appearance:
Solid
Purity:
99.4%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
CEP-33779 is a selective inhibitor that effectively regulates the immune response by intervening in the JAK signaling pathway.
Synonym:
1257704-57-6; CEP33779; CEP-33779; N-(3-(4-Methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; N-[3-(4-Methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; [1,2,4]Triazolo[1,5-a]pyridin-2-amine, N-[3-(4-methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-; 8-[4-(Methanesulfonyl)phenyl]-N-[3-(4-methylpiperazin-1-yl)phenyl][1,2,4]triazolo[1,5-a]pyridin-2-amine; N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[1,5-a]pyridin-2-amine
CAS No.:
1257704-57-6
Compound CID:
57336812
Formula:
C24H26N6O2S
Formula Weight:
462.57
Specification
Targets & IC50:
JAK2: 1.8±0.6 nM
Relative Density:
1.35 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
CEP-33779 can be used in autoimmune disease and some cancer studies.
Library Information
Targets:
JAK
Receptors:
JAK; JAK2
Pathways:
Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem cells
Plate Number:
AOCL-18
Plate Location:
e7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
16.67 mg/mL; 36.03 mM
ALogP:
3.86
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
5
