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SB-505124
Cat. No.:
OB0225LY-0203
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
SB-505124 is a TGF-β receptor kinase inhibitor that selectively inhibits the TGF-β signaling pathway.
Synonym:
694433-59-5; SB-505124; 2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine; TGF-beta RI inhibitor III; 2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl)-6-methylpyridine; 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine; 2-(5-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-4-yl)-6-methylpyridine; 2-[4-(2H-1,3-Benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine
CAS No.:
694433-59-5
Compound CID:
9858940
Formula:
C20H21N3O2
Formula Weight:
335.4
Specification
Relative Density:
1.202 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SB-505124 can be used to study the important role of relevant signaling pathways in cell differentiation and cancer development.
Library Information
Targets:
ALK family
Receptors:
ALK4; ALK5
Pathways:
Angiogenesis; Stem cells; Tyrosine kinase/adaptors; TGF-β/Smad signaling
Plate Number:
AOCL-3
Plate Location:
e7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 149.08 mM
Special Max Solubility:
1eq. HCl: 33.5 mg/mL
ALogP:
4.609
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
3
