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Staurosporine
Cat. No.:
OB0125LY-070
Appearance:
Solid
Purity:
99.8%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
Staurosporine is a broad-spectrum protein kinase inhibitor originally isolated from a microorganism. It inhibits a variety of kinases such as PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2.
Synonym:
62996-74-1; Antibiotic AM-2282; AM-2282; CGP 41251; Staurosporin; (+)-Staurosporine; (2S,3R,4R,6R)-3-Methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
CAS No.:
62996-74-1
Compound CID:
44259
Formula:
C28H26N4O3
Formula Weight:
466.53
Specification
Targets & IC50:
PKCη: 4 nM; PKCδ: 20 nM; PKCγ: 5 nM; PKCα: 2 nM; PKCε: 73 nM; PKCζ: 1086 nM
Relative Density:
1.56 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Staurosporine can be used in neuroscience research to explore its potential role in apoptosis and neuroprotection.
Library Information
Targets:
Apoptosis; Src; Antibiotic; PKA; Antifungal; PKC; Antibacterial
Receptors:
Antibiotic; Apoptosis; Bacterial; c-Fgr; Fungal; PKA; PKC; PKCα; PKCγ; PKCη
Pathways:
Angiogenesis; Chromatin/Epigenetic; Apoptosis; Tyrosine kinase/adaptors; Cytoskeletal signaling; Microbiology/Virology
Plate Number:
AOCL-4
Plate Location:
a3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
13.75 mg/mL; 29.47 mM
Water Max Solubility:
0.1 mg/mL
Saline Max Solubility:
3.1 mg/mL; 6.64 mM
