Cucurbitacin B

Cat. No.: OB0225LY-0294

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Cucurbitacin B is a tetracyclic compound derived from plants with a variety of biological activities, including anti-tumor and anti-inflammatory effects.

Synonym: Cuc B; Amarine; 6199-67-3; Datisca principle B; (+)-Cucurbitacin B; Cucurbitacine B; 1,2-Dihydro-alpha-elaterin; [(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-Dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate

CAS No.: 6199-67-3

Compound CID: 5281316

Formula: C₃₂H₄₆O₈

Formula Weight: 558.7

Specification

Relative Density: 1.0953 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Cucurbitacin B can be used to study cancer biology or play an important role in the study of anti-inflammatory mechanisms.

Library Information

Targets: Transcription factors; Phosphatases/Tumor suppressors; Cell adhesion molecules/cytoskeletal proteins

Receptors: HIF-1; Integrin; PTEN; STAT3

Pathways: Angiogenesis; PI3K/Akt/mTOR signaling; Metabolism; Autophagy; Chromatin/Epigenetic; Apoptosis; Cytoskeletal signaling; Stem cells; JAK/STAT signaling

Plate Number: AOCL-4

Plate Location: g5

Empty Location: a1-h1; a12-h12

Container: 96-well plate

Formulation: 10 mM DMSO

DMSO Max Solubility: 91 mg/mL; 162.9 mM

Ethanol Max Solubility: 50 mg/mL; 89.49 mM

Solubility: Soluble in chloroform, dichloromethane, and ethyl acetate.