URMC-099

Cat. No.: OB0225LY-0448

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: URMC-099 is a novel drug specifically designed to inhibit histone deacetylase (HDAC), thereby affecting gene expression and cellular function.

Synonym: 1229582-33-5; 3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine; 3-(1H-Indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine; 3-(1H-Indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine

CAS No.: 1229582-33-5

Compound CID: 54764565

Formula: C₂₇H₂₇N₅

Formula Weight: 421.54

Specification

Relative Density: 1.256 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: URMC-099 can be used in gene expression regulation studies to help understand the role of histone deacetylation in cell biology.

Library Information

Targets: Kinases

Receptors: Abl1; Aurora A; Aurora B; Aurora C; c-Met; CDK1; CDK2; DLK; IGF-1R; Insulin receptor; Lck; LRRK2; MEKK2; Mixed lineage kinase; MLK1; MLK2; MLK3; ROCK1; ROCK2; SGK; SGK1; Syk; TrkA; TrkB; VEGFR1/FLT1

Pathways: Angiogenesis; MAPK; DNA damage/DNA repair; Autophagy; Chromatin/Epigenetic; Cell cycle/Checkpoint; Stem cells; Metabolism; Tyrosine kinase/adaptors; Cytoskeletal signaling

Plate Number: AOCL-6

Plate Location: g5

Empty Location: a1-h1; a12-h12

Container: 96-well plate

Formulation: 10 mM DMSO

DMSO Max Solubility: 75 mg/mL; 177.9 mM

Water Max Solubility: <1 mg/mL (insoluble or slightly soluble)

Ethanol Max Solubility: 6 mg/mL; 14.2 mM