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DMH-1
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Cat. No.:
OB0125LY-069
Size:
5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg
CAS No.:
1206711-16-1
Compound CID:
50997747
Specification
Description:
DMH-1 is a small molecule compound that blocks BMP signaling by inhibiting the phosphorylation activity of Smad1 and Smad5.
Formula Weight:
380.44
Stability:
3 years in powder form.
Applications:
DMH-1 can be used to explore the role of BMP in different physiological and pathological conditions and its importance in cell differentiation, tissue formation and development.
Storage:
Storage at -20°C.
Formula:
C24H20N4O
Appearance:
Solid
Purity:
99.9%
Identity:
Confirmed by NMR and HPLC.
Targets&IC50:
ALK2: 107.9 nM
Relative Density:
1.24 g/cm3
Library Information
Plate Number:
AOCL-3
Plate Location:
c7
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Angiogenesis; Autophagy; Tyrosine kinase/adaptors; Stem cells
Targets:
ALK; TGF-beta/Smad; Autophagy
Receptors:
ALK2; Autophagy; TGF-β receptor
DMSO Max Solubility (mg/mL):
12.5 mg/mL
DMSO Max Solubility (mM):
32.86 mM
Water Max Solubility (mg/mL):
1 mg/mL
Ethanol Max Solubility (mg/mL):
1 mg/mL
Saline Max Solubility (mg/mL):
1.25 mg/mL
Saline Max Solubility (mM):
3.29 mM
ALogP:
4.036
HBA_Count:
4
Rotatable Bond:
4