Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
Garcinone D
Cat. No.:
0225LY-0963
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Garcinone D demonstrates targeted microsomal aromatase inhibition and p65 activation suppression (IC50: 3.2 μM), while exhibiting significant cytotoxicity against CEM-SS cells (IC50: 3.2 μg/ml).
Synonym:
107390-08-9; 1,3,6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methylbut-2-enyl)xanthen-9-one; Garcinone-D; Garcinia mangostana (Mangosteen); 1,3,6-trihydroxy-8-(3-hydroxy-3-methyl-butyl)-7-methoxy-2-(3-methylbut-2-enyl)xanthen-9-one; 9H-Xanthen-9-one, 1,3,6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methyl-2-butenyl)-
CAS No.:
107390-08-9
Compound CID:
5495926
Formula:
C24H28O7
Formula Weight:
428.47
Specification
Relative Density:
1.304 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Garcinone D can be used in oncology research to investigate its anti-proliferative effects against diverse cancer cell lines.
Library Information
Target:
STAT; Nrf2
Receptor:
Keap1-Nrf2; STAT3
Pathways:
Stem cell regulation; Immunology/Inflammation; JAK/STAT signaling; Metabolism; NF-κB
Plate Number:
AOCL-13
Plate Location:
d4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 116.69 mM
