GSK3-IN-4

Cat. No.: OB0225WX-2162

Appearance: Solid

Purity: ≥97%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: GSK3-IN-4 is a dual inhibitor of the GSK-3 alpha and beta isoforms, demonstrating inhibitory potency within a range of 0.101 to 1 μM as measured by Caliper assay.

Synonym: 748145-19-9; 3,7,7-trimethyl-4-(3-pyridinyl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one; 3,7,7-Trimethyl-4-(pyridin-3-yl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one; GSK3-IN-4; 3,7,7-trimethyl-4-(pyridin-3-yl)-2H,4H,5H,6H,7H,8H,9H-pyrazolo[3,4-b]quinolin-5-one; 5H-Pyrazolo[3,4-b]quinolin-5-one, 1,4,6,7,8,9-hexahydro-3,7,7-trimethyl-4-(3-pyridinyl)-; 3,7,7-trimethyl-4-pyridin-3-yl-4,6,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5-one; 1,2,4,6,7,8-Hexahydro-3,7,7-trimethyl-4-(3-pyridinyl)-5H-pyrazolo[3,4-b]quinolin-5-one; 3,7,7-trimethyl-4-(pyridin-3-yl)-2H,4H,6H,8H,9H-pyrazolo[3,4-b]quinolin-5-one; 3,7,7-Trimethyl-4-(pyridin-3-yl)-1,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one

CAS No.: 748145-19-9

Compound CID: 3809721

Formula: C₁₈H₂₀N₄

Formula Weight: 308.38

Specification

Relative Density: 1.28 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: GSK3-IN-4 is applied in molecular biology experiments to explore the biological consequences of rapid GSK-3 inhibition on the stability of the beta-catenin destruction complex.