NVP-TNKS656

Cat. No.: OB0225WX-1701

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and LC-MS.

Size:

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Product Overview

Description: NVP-TNKS656 is a highly potent and selective TNKS2 inhibitor characterized by its oral bioavailability and exceptional inhibitory activity.

Synonym: TNKS656; 1419949-20-4; NVP-TNKS656; 1419949-20-4; TNKS656; NVP-TNKS-656; TNKS-656; N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide; 1-Piperidineacetamide, N-(cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-; N-(Cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide; N-(Cyclopropylmethyl)-2-(4-(4-methoxybenzoyl)piperidin-1-yl)-N-((4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl)acetamide; N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-({4-oxo-3H,4H,5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl}methyl)acetamide; N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-({4-oxo-1H,5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl}methyl)acetamide; N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-({4-oxo-3H,5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl}methyl)acetamide; N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-1,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide; N-(Cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-1-piperidineacetamide; N-Cyclopropylmethyl-2-[4-(4-methoxy-benzoyl)-piperidin-1-yl]-N-(4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-ylmethyl)-acetamide; N-Cyclopropylmethyl-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-4,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide

CAS No.: 1419949-20-4

Compound CID: 136237316

Formula: C₂₇H₃₄N₄O₅

Formula Weight: 494.58

Specification

Targets&IC50: TNKS2: 6 nM

Relative Density: 1.37 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: NVP-TNKS656 is used in drug discovery as a highly selective and orally bioavailable tankyrase inhibitor to study the regulation of telomere length and Wnt signaling pathways.