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IQ 1
Cat. No.:
OB0225WX-1704
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
IQ 1 is a multifunctional small molecule that blocks PP2A/Nkd interactions and reduces Wnt-stimulated phosphorylation to maintain the pluripotency of mouse embryonic stem cells (ESCs).
Synonym:
IQ1; IQ-1; 331001-62-8; IQ 1; 2-(4-Acetyl-phenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide; 2-((4-Acetylphenyl)hydrazinylidene)-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide; 2-(2-(4-Acetylphenyl)diazenyl)-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide; Acetamide, 2-(2-(4-acetylphenyl)diazenyl)-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-; 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide; MFCD00354369
CAS No.:
331001-62-8
Compound CID:
5823908
Formula:
C21H22N4O2
Formula Weight:
362.42
Specification
Relative Density:
1.23 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
IQ 1 is employed in stem cell biology to study the maintenance of pluripotency in embryonic stem cells by modulating the interaction between beta-catenin and specific co-activators.
Library Information
Target:
Wnt/β-Catenin
Receptor:
Wnt
Pathways:
Stem cells; Cytoskeletal signaling
Plate Number:
AOCL-22
Plate Location:
g9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
45 mg/mL; 124.17 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
7 mg/mL; 19.31 mM
ALogP:
3.005
HBA_Count:
4
HBD_Count:
2
Rotatable Bond:
4
