AdipoUpX™ Human RETN MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human RETN MSCV Particle (Overexpression) is a stable integration tool for the specific and efficient overexpression of the human RETN (Resistin) gene. Resistin is an adipokine that links obesity to insulin resistance and chronic inflammation. This stable system is optimized for hematopoietic stem cells, stem cells, etc., making it a perfect tool for studying immunometabolism in permanent macrophage or adipocyte cell lines. Comprehensive quality control, including titer and sterility validation, ensures the safety and performance of every batch for metabolic research.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: RETN

Full Name: Resistin

Gene Symbol: ADSF; RENT; RSTN; XCP1; FIZZ3; RETN1

Gene ID: 56729

RefSeq ID-1: NP_001180303.1

RefSeq ID-2: NM_001193374.2

Summary: RETN encodes a protein belonging to the resistin-like family, characterized structurally by a distinctive C-terminal arrangement of ten cysteine residues. While the rodent homolog secreted by adipocytes strongly links obesity to Type II diabetes by impairing insulin action, the human protein's function is more diverse. Beyond potential metabolic roles, human RETN exhibits potent antimicrobial activity on the skin, acting as a defense against both Gram-positive and Gram-negative bacteria. This duality underscores a complex biological role spanning metabolic balance and innate host defense.

AdipoUpX™ Human RETN MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products