Product Overview
Description:
AdipoUpX™ Human MYT1L MSCV Particle (Overexpression) is a high-titer MSCV particle designed for the specific and efficient stable expression of the human MYT1L gene. MYT1L is a neuronal transcription factor that safeguards neuronal identity and is linked to early-onset obesity and intellectual disability. This stable integration system is optimized for stem cells and other mammalian lineages, making it an ideal tool for investigating neurodevelopmental metabolic regulation. Product quality is ensured by comprehensive quality control validation across all viral lots.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
MYT1L
Full Name:
Myelin transcription factor 1 like
Gene Symbol:
NZF1; MRD39; myT1-L; ZC2H2C2; ZC2HC4B
Summary:
MYT1L encodes a neuronal-specific zinc finger transcription factor involved in central nervous system development. Together with other transcription factors, MYT1L can reprogram human fibroblasts into functional neurons. Mutations in this gene are linked to autosomal dominant cognitive disabilities and autism spectrum disorder. Alternative splicing produces multiple transcript variants.
