AdipoUpX™ Human PRMT7 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human PRMT7 MSCV Particle (Overexpression) is a powerful gene delivery tool designed for the long-term stable overexpression of the human PRMT7 gene. PRMT7-mediated protein methylation is an emerging regulator of muscle metabolism and adipogenesis. The MSCV backbone is optimized for hematopoietic stem cells, stem cells, etc., providing a robust platform for epigenetic research in obesity models. This product supports flexible customization of functional components and passes comprehensive quality control to ensure high performance and safety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: PRMT7

Full Name: Protein arginine methyltransferase 7

Gene Symbol: SBIDDS

Gene ID: 54496

RefSeq ID-1: NP_001171753.1

RefSeq ID-2: NM_001184824.4

Summary: PRMT7 encodes a protein arginine N-methyltransferase that catalyzes monomethylation of arginine residues on histones and other substrates. This enzyme is involved in neuronal differentiation, male germline imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of Wnt signaling. Mutations in PRMT7 lead to syndromes featuring intellectual disability, short stature, and other abnormalities. Additionally, the protein may promote breast cancer cell invasion and metastasis.

AdipoUpX™ Human PRMT7 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

Related Products