Products
Online Inquiry
(±)-Praeruptorin A
Cat. No.:
OB0225WX-1640
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
(±)-Praeruptorin A is a coumarin derivative that interferes with p38/Akt-c-Fos-NFATc1 signaling and calmodulin-dependent pathways to inhibit calcium oscillations and modulate eicosanoid formation.
Synonym:
Praeruptorin A; (-)-Praeruptorin A; 73069-25-7; Praeruptorin A; 2-Butenoic acid, 2-methyl-,(9S,10S)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2Z)-; CCRIS 7247; ( inverted exclamation markA)-Praeruptorin A; [(9S,10S)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (Z)-2-methylbut-2-enoate; (+/-)-Praeruptorin A; MFCD23105643; [(9S,10S)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-]chromen-9-yl] (Z)-2-methylbut-2-enoate
CAS No.:
73069-25-7
Compound CID:
38347607
Formula:
C21H22O7
Formula Weight:
386.4
Specification
Relative Density:
1.28 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
(+/-)-Praeruptorin A is applied in cardiovascular and neuroprotection research to examine the modulation of calcium channels and the inhibition of inflammatory responses in cellular models.
Library Information
Target:
Calcium channel; p38 MAPK; Akt
Receptor:
Akt; Calcium channel; p38
Pathways:
Cytoskeletal signaling; Membrane transporter/Ion channel; MAPK; Metabolism; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-22
Plate Location:
a5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
70 mg/mL; 181.2 mM
Ethanol Max Solubility:
Soluble
Solubility:
Soluble in pyridine, methanol, etc.
ALogP:
3.502
HBA_Count:
7
HBD_Count:
0
Rotatable Bond:
5
