Salinomycin

Cat. No.: 0225LY-1302

Appearance: Solid

Purity: ≥98%

Identity: Confirmed by NMR, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Salinomycin acts as a polyether potassium ionophore antibiotic that restricts the growth of gram-positive bacteria; it also functions as a powerful Wnt/beta-catenin signaling inhibitor by preventing Wnt-induced LRP6 phosphorylation and specifically targets human cancer stem cells.

Synonym: Procoxacin; 53003-10-4; Coxistac; Salinomicina; Salinomycine; Salinomycinum; Bio-cox; (2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid; 1,6,8-Trioxadispiro[4.1.5.3]pentadecane, salinomycin deriv.; Stereoisomer of a-ethyl-6-[5-[2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxoheptyl]tetrahydro-5-methyl-2H-pyran-2-acetic acid

CAS No.: 53003-10-4

Compound CID: 3085092

Formula: C₄₂H₇₀O₁₁

Formula Weight: 751

Specification

Relative Density: 1.18 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Salinomycin can be used in cancer research to investigate the selective elimination of cancer stem cells and its role in disrupting ion transport across biological membranes.