Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
Hederacolchiside A1
Cat. No.:
0225LY-0575
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
Add to basket
Product Overview
Description:
Hederacolchiside A1 exhibits anti-leishmanial and antiproliferative activities by altering parasite membrane integrity; it also targets cancer cells (IC50: 2.4 μM), particularly pigmented melanoma, by inducing apoptosis via the PI3K/Akt/mTOR pathway.
Synonym:
Raddeanoside R13; 106577-39-3; (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-4-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-((2S,3R,4S,5S)-4-hydroxy-5-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-3-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl)oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
CAS No.:
106577-39-3
Compound CID:
11622076
Formula:
C47H76O16
Formula Weight:
897.1
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Hederacolchiside A1 can be used in cancer biology to investigate its role in inducing apoptosis and inhibiting the PI3K/Akt/mTOR pathway.
Library Information
Target:
PI3K; ERK; Parasite protein; mTOR; MEK; Akt
Receptor:
Akt; ERK; MEK; mTOR; Parasite protein; PI3K
Pathways:
Cytoskeletal signaling; MAPK; Microbiology/Virology; Apoptosis; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-8
Plate Location:
d9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
250 mg/mL; 278.68 mM





