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Vincristine
Cat. No.:
0225LY-0569
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Vincristine binds to tubulin to disrupt microtubule formation and mitosis, serving as a microtubule-destabilizing agent for the study of hematologic malignancies like leukemia.
Synonym:
57-22-7; 22-Oxovincaleukoblastine; Leurocristine; Vinkristin; Vincrystine; Leucristine; Tecnocris; Oncovine; Methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
CAS No.:
57-22-7
Compound CID:
5978
Formula:
C46H56N4O10
Formula Weight:
824.96
Specification
Relative Density:
1.1539 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Vincristine can be used in tubulin research, particularly in studying the disruption of microtubule assembly during mitosis.
Library Information
Target:
JNK; Akt; ERK; NF-κB; p38 MAPK; mTOR
Receptor:
Akt; ERK; JNK; mTOR; NF-κB; p38 MAPK
Pathways:
Cytoskeletal signaling; PI3K/Akt/mTOR signaling; MAPK; NF-κB
Plate Number:
AOCL-8
Plate Location:
d3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
12 mg/mL; 14.55 mM
