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K-80003
Cat. No.:
0225LY-1110
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
K-80003 is a potent regulator of retinoid X receptor-alpha that hinders tumor cell proliferation and TRxrα-mediated Akt activation.
Synonym:
1292821-90-9; [5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid; 2-[(3Z)-6-fluoro-2-methyl-3-[(4-propan-2-ylphenyl)methylidene]inden-1-yl]acetic acid; 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(1-methylethyl)phenyl)methylene)-, (1Z)-; [(1Z)-5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl]acetic acid
CAS No.:
1292821-90-9
Compound CID:
46224594
Formula:
C22H21FO2
Formula Weight:
336.4
Specification
Relative Density:
1.192 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
K-80003 can be used in cancer therapy research to explore the targeting of truncated RXR-alpha for the suppression of tumor growth.
Library Information
Target:
RAR/RXR ; Akt
Receptor:
Retinoid X receptor α; Akt
Pathways:
Cytoskeletal signaling; Metabolism; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-15
Plate Location:
c6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
60 mg/mL; 178.36 mM
