Products
- Anti-Obesity Compound Library
- GPCR/G Protein-Targeted Compounds
- Immunology/Inflammation-Targeted Compounds
- JAK/STAT-Targeted Compounds
- MAPK-Targeted Compounds
- Membrane Transporter/Ion Channel-Targeted Compounds
- Metabolism-Targeted Compounds
- NF-κB-Targeted Compounds
- Microbiology/Virology-Targeted Compounds
- Neuronal Signaling-Targeted Compounds
- PI3K/Akt/mTOR-Targeted Compounds
- Oxidation-reduction-Targeted Compounds
- Proteases/Proteasome-Targeted Compounds
- Stem Cells/Wnt-Targeted Compounds
- Tyrosine Kinase/Adaptors-Targeted Compounds
- Ubiquitin-Targeted Compounds
Online Inquiry
(-)-Butin
Cat. No.:
0225LY-1442
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
Add to basket
Product Overview
Description:
(-)-Butin provides cellular protection against H2O2-induced damage and mitochondrial dysfunction by stimulating Nrf2-mediated Mn SOD induction through the PI3K/Akt pathway.
Synonym:
Butin; 492-14-8; 7,3',4'-Trihydroxyflavanone; (2S)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrochromen-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (S)-; (2S)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-4H-chromen-4-one
CAS No.:
492-14-8
Compound CID:
92775
Formula:
C15H12O5
Formula Weight:
272.25
Specification
Relative Density:
1.485 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
(-)-Butin can be used in antioxidant research to investigate its role in protecting cells from free radical-induced oxidative injury.
Library Information
Target:
PI3K; Akt; Nrf2
Receptor:
PI3K; Akt; Nrf2
Pathways:
Cytoskeletal signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-19
Plate Location:
e5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 183.65 mM
