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Deltonin
Cat. No.:
0225LY-1387
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
Deltonin demonstrates cytotoxic activity against HepG2 and MDA-MB-231 cancer cells by inhibiting the activation of the AKT and ERK1/2 pathways.
Synonym:
55659-75-1; (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol; (3beta,25R)-Spirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-4))-beta-D-glucopyranoside; Beta-D-Glucopyranoside, (3beta,25R)-spirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-4))-
CAS No.:
55659-75-1
Compound CID:
441884
Formula:
C45H72O17
Formula Weight:
885.04
Specification
Targets&IC50:
C26 cells (mouse): 1.22 μM; MDA-MB-231 cells (human): 1.58 μM; HepG2 cells: 7.66 μM
Relative Density:
1.42 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Deltonin can be used in oncology research to study the induction of apoptosis and the inhibition of cell growth in various cancer types.
Library Information
Target:
Akt; ERK
Receptor:
Akt; ERK
Pathways:
Cytoskeletal signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-18
Plate Location:
g10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
100 mg/mL; 112.99 mM
Water Max Solubility:
<1 mg/mL (insoluble)





