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PD 198306
Cat. No.:
OB0225WX-1795
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
PD 198306 is a selective antagonist of MAPK/ERK-kinase (MEK) that modulates signaling by preventing the increase of activated ERK1 levels.
Synonym:
212631-61-3; PD-198306; Benzamide, N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-((4-iodo-2-methylphenyl)amino)-; N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-(4-iodo-2-methylanilino)benzamide; N-Cyclopropylmethoxy-3,4,5-trifluoro-2-(4-iodo-2-methylphenylamino)benzamide; N-(Cyclopropylmethoxy)-3,4,5-trifluoro-2-((4-iodo-2-methylphenyl)amino)benzamide; N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-[(4-iodo-2-methylphenyl)amino]benzamide
CAS No.:
212631-61-3
Compound CID:
9956637
Formula:
C18H16F3IN2O2
Formula Weight:
476.23
Specification
Relative Density:
1.686 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PD 198306 is used in neurological research as a selective MEK1/2 inhibitor to investigate the role of the MAPK pathway in pain signaling and neuroinflammatory responses.
Library Information
Target:
MEK
Receptor:
MEK
Pathways:
MAPK
Plate Number:
AOCL-24
Plate Location:
a2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
45 mg/mL; 94.49 mM
