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PP58
Cat. No.:
0225LY-1109
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
PP58 functions as an inhibitor designed to target the Src family, FGFR, and PDGFR.
Synonym:
212391-58-7; 2-[4-(2-aminoethoxy)anilino]-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7-one; Pyrido[2,3-d]pyrimidin-7(8H)-one,2-[[4-(2-aminoethoxy)phenyl]amino]-6-(2,6-dichlorophenyl)-8-methyl-; 2-((4-(2-Aminoethoxy)phenyl)amino)-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one; PP 58; 2-[[4-(2-Aminoethoxy)phenyl]amino]-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one; 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 58
CAS No.:
212391-58-7
Compound CID:
5327904
Formula:
C22H19Cl2N5O2
Formula Weight:
456.32
Specification
Relative Density:
1.426 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
PP58 can be used in biochemical studies to examine the potent and selective inhibition of the PDGFR tyrosine kinase family.
Library Information
Target:
p38 MAPK; FGFR; PDGFR; Src; TNF
Receptor:
PDGFR; FGFR; Src; p38; TNF-α
Pathways:
MAPK; Angiogenesis; Apoptosis; Tyrosine kinase/adaptors
Plate Number:
AOCL-15
Plate Location:
c5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
56.3 mg/mL; 123.38 mM
