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(E/Z)-BIX02188
Cat. No.:
OB0225LY-0215
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
(E/Z)-BIX02188 is a specific MEK5 inhibitor that inhibits ERK5 catalytic activity.
Synonym:
1094614-84-2; BIX02188; BIX-02188; BIX 02188; (Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxamide; (3Z)-3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indole-6-carboxamide; 3-[N-[3-[(dimethylamino)methyl]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-1H-indole-6-carboxamide
CAS No.:
1094614-84-2
Compound CID:
135398492
Formula:
C25H24N4O2
Formula Weight:
412.48
Specification
Relative Density:
1.283 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
(E/Z)-BIX02188 can be used for cellular metabolic signaling studies.
Library Information
Targets:
TGF-beta/Smad; MEK; ERK
Receptors:
ERK5; MEK1; MEK2; MEK5; TGFβR1
Pathways:
MAPK; Stem cells
Plate Number:
AOCL-3
Plate Location:
f9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
40 mg/mL; 97 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
3 mg/mL; 7.27 mM
