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OSI-930
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Cat. No.:
OB0125LY-079
Size:
1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg
CAS No.:
728033-96-3
Compound CID:
9868037
Specification
Description:
OSI-930 is a small molecule inhibitor with anti-tumor activity that primarily targets certain tyrosine kinases.
Formula Weight:
443.44
Stability:
3 years in powder form.
Applications:
OSI-930 can be used for drug development for tumor-related diseases.
Storage:
Storage at -20°C.
Formula:
C22H16F3N3O2S
Appearance:
Solid
Purity:
99.7%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Targets&IC50:
CSF1R: 15 nM; FLK1: 8 nM; KDR: 9 nM; C-Raf: 41 nM; Lck: 22 nM
Relative Density:
1.450 g/cm3
Library Information
Plate Number:
AOCL-10
Plate Location:
h4
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Apoptosis; Angiogenesis; MAPK; Tyrosine kinase/adaptors
Targets:
CSF-1R; Src; c-Kit; Apoptosis; Raf; c-Fms; VEGFR; FLT
Receptors:
Apoptosis; c-Fms; c-Kit; C-Raf; CSF-1R; FLT1; Lck; VEGFR; VEGFR2 (KDR)
DMSO Max Solubility (mg/mL):
82 mg/mL
DMSO Max Solubility (mM):
184.9 mM
Ethanol Max Solubility (mg/mL):
3 mg/mL
Ethanol Max Solubility (mM):
6.76 mM
ALogP:
6.266
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
7