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Calycosin
Cat. No.:
OB0225WX-1906
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Calycosin functions as a selective estrogen receptor modulator (SERM) that inhibits tyrosinase activity (IC50: 38.4 microM) and regulates cellular growth through ER-beta-dependent modulation of the Akt, PI3K, and p38 MAPK pathways.
Synonym:
Cyclosin; 3'-Hydroxyformononetin; 20575-57-9; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one; 3',7-dihydroxy-4'-methoxyisoflavone; 7,3'-dihydroxy-4'-methoxyisoflavone; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-; HSDB 8109; 3'-hydroxy-formononetin; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
CAS No.:
20575-57-9
Compound CID:
5280448
Formula:
C16H12O5
Formula Weight:
284.26
Specification
Relative Density:
1.42 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Calycosin is applied in traditional medicine and metabolic research to examine its estrogenic activities and its protective effects against oxidative stress and inflammatory injury in vascular cells.
Library Information
Target:
Tyrosinase
Receptor:
Tyrosinase
Pathways:
Apoptosis; Proteases/Proteasome
Plate Number:
AOCL-25
Plate Location:
d8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
52 mg/mL; 182.9 mM
Solubility:
Soluble in chloroform, dichloromethane, ethyl acetate, acetone, etc.
