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K-Ras(G12C) inhibitor 12
Cat. No.:
OB0225LY-0063
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
Add to basket
Product Overview
Description:
K-Ras(G12C) inhibitor 12 is a small molecule compound specifically designed to inhibit the K-Ras (G12C) mutation by binding to it and blocking its interaction with downstream effector proteins.
Synonym:
1469337-95-8; 1-(4-(2-((4-Chloro-2-hydroxy-5-iodophenyl)amino)acetyl)piperazin-1-yl)prop-2-en-1-one; 1-(4-(2-(4-Chloro-2-hydroxy-5-iodophenylamino)acetyl)piperazin-1-yl)prop-2-en-1-one; 1-(4-(2-(4-Chloro-2-hydroxy-5-iodophenylamino)-acetyl)piperazin-1-yl)prop-2-en-1-one; 1-[4-[2-(4-Chloro-2-hydroxy-5-iodoanilino)acetyl]piperazin-1-yl]prop-2-en-1-one; 2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-
CAS No.:
1469337-95-8
Compound CID:
73555129
Formula:
C15H17ClIN3O3
Formula Weight:
449.67
Specification
Relative Density:
1.736 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
K-Ras(G12C) inhibitor 12 is critical in cancer biology research, especially in targeting variants of the K-Ras (G12C) protein.
Library Information
Targets:
Raf; Apoptosis; Ras
Receptors:
K-Ras(G12C)
Pathways:
Apoptosis; GPCR/G protein; MAPK
Plate Number:
AOCL-1
Plate Location:
g5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
26 mg/mL; 57.8 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)





