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ISRIB
Cat. No.:
OB0125LY-082
Appearance:
Solid
Purity:
99.9%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
ISRIB is a potent and selective PERK inhibitor that inhibits the activation of cellular responses to stress.
Synonym:
548470-11-7; ISRIB; ISRIB (trans-isomer); N,N'-(cis-Cyclohexane-1,4-diyl)bis (2-(4-chlorophenoxy)acetamide); ISRIB trans-isomer; 2-(4-Chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide; N,N'-(Cyclohexane-1,4-diyl)bis (2-(4-chlorophenoxy)acetamide); N,N'-Cyclohexane-1,4-diylbis[2-(4-chlorophenoxy)acetamide]; 2-(4-Chlorophenoxy)-N-[ (1r,4r)-4-[2-(4-chlorophenoxy)acetamido]cyclohexyl]acetamide
CAS No.:
548470-11-7
Compound CID:
1011240
Formula:
C22H24Cl2N2O4
Formula Weight:
451.34
Specification
Relative Density:
1.33 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
ISRIB is mainly used in the field of neuroscience.
Library Information
Targets:
PERK
Receptors:
PERK
Pathways:
Apoptosis
Plate Number:
AOCL-15
Plate Location:
g8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
4.51 mg/mL; 10 mM
