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4-MMPB
Cat. No.:
OB0225WX-1845
Appearance:
Solid
Purity:
≥97%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
4-MMPB is a selective 15-lipoxygenase antagonist with measured IC50 values of 19.1 μM for the human 15-LOX-1 isoform and 19.5 μM for soybean 15-lipoxygenase.
Synonym:
15-Lipoxygenase Inhibitor 1; 928853-86-5; 15-Lipoxygenase Inhibitor I; 4-MMPB; 4-Methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine; 4-Methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine; 4-methyl-2-(4-methylpiperazin-1-yl)pyrimido[4,5-b][1,4]benzothiazine
CAS No.:
928853-86-5
Compound CID:
44423602
Formula:
C16H19N5S
Formula Weight:
313.42
Specification
Targets&IC50:
Others: 69.6 μM
Relative Density:
1.265 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
4-MMPB is utilized in signal transduction research as a chemical tool to study the selective inhibition of targeted enzymes within the lipoxygenase pathway and their impact on cell survival.
Library Information
Target:
Lipoxygenase
Receptor:
Lipoxygenase
Pathways:
Apoptosis; Metabolism
Plate Number:
AOCL-24
Plate Location:
f6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
8 mg/mL; 25.52 mM
