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Tauroursodeoxycholate
Cat. No.:
0225LY-1414
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
Tauroursodeoxycholate is a highly soluble tertiary bile acid found in low levels in humans; as a more hydrophilic version of ursodeoxycholic acid, it is currently under investigation for treating conditions like ALS, cystic fibrosis, cholestasis, and primary biliary cirrhosis.
Synonym:
Taurolite; Tauroursodeoxycholic acid; UR 906; Ursodeoxycholyltaurine; TUDCA; 14605-22-2; Ursodeoxycholyltaurine; Taurursodiol; Taurolite; N-ursodeoxycholoyltaurine; N-(3alpha,7beta-dihydroxy-5beta-cholan-24-oyl)-taurine; Taurine, N-(3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oyl)-,; Relyvrio (sodium phenylbutyrate + taurursodiol); 2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl)amino)ethanesulfonic acid; 2-[(4R)-4-[(1S,2S,5R,7S,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid; N-(3alpha,7beta-dihydroxy-5beta-cholan-24-oyl)taurine; 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid N-(2-sulfoethyl)amide; 2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl) amino)ethanesulfonic acid; 2-[(3alpha,7beta-dihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonic acid; 2-{[(3alpha,5beta,7beta)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethane-1-sulfonic acid
CAS No.:
14605-22-2
Compound CID:
9848818
Formula:
C26H45NO6S
Formula Weight:
499.7
Specification
Relative Density:
1.216 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Tauroursodeoxycholate can be used in cell biology research to study the inhibition of endoplasmic reticulum (ER) stress and the prevention of apoptosis.
Library Information
Target:
ERK; Caspase; Cytochrome P450
Receptor:
ERK; Caspase-3; CYP3A
Pathways:
Apoptosis; Metabolism; MAPK; Proteases/Proteasome
Plate Number:
AOCL-19
Plate Location:
b7
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
6.25 mg/mL; 12.51 mM
Water Max Solubility:
100 mg/mL; 200.12 mM





