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Kahweol
Cat. No.:
0225LY-1017
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Kahweol possesses anti-angiogenic and anticarcinogenic properties, allowing it to hinder LPS-induced NF-κB activation by inhibiting IκB kinase activity.
Synonym:
6894-43-5; CCRIS 1521; KX95B6688Y; (3bS,5aS,7R,8R,10aR,10bS)-7-(hydroxymethyl)-10b-methyl-3b,4,5,6,7,8,9,10,10a,10b-decahydro-5a,8-methanocyclohepta[5,6]naphtho[2,1-b]furan-7-ol; (1S,4S,12S,13R,16R,17R)-17-(hydroxymethyl)-12-methyl-8-oxapentacyclo[14.2.1.01,13.04,12.05,9]nonadeca-5(9),6,10-trien-17-ol; 5a,8-Methano-5aH-cyclohepta(5,6)naphtho(2,1-b)furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS,5aS,7R,8R,10aR,10bS)-; 5a,8-Methano-5aH-cyclohepta(5,6)naphtho(2,1-b)furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-; 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, (3bS,5aS,7R,8R,10aR,10bS)-; 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol, 3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-, [3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-
CAS No.:
6894-43-5
Compound CID:
114778
Formula:
C20H26O3
Formula Weight:
314.42
Specification
Relative Density:
1.25 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Kahweol can be used in bone biology research to investigate the inhibition of osteoclast differentiation and its anti-resorptive effects.
Library Information
Target:
NF-κB; AMPK
Receptor:
NF-κB; AMPK
Pathways:
Apoptosis; PI3K/Akt/mTOR signaling; Chromatin/Epigenetic; NF-κB
Plate Number:
AOCL-14
Plate Location:
a10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
36.25 mg/mL; 115.29 mM





