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Vitamin B12 test kit

Zileuton

Cat. No.: OB0225WX-1597
Appearance: Solid
Purity: ≥99%
Identity: Confirmed by NMR, and LC-MS.
Size:
Zileuton
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Product Overview

Description: Zileuton is a synthetic hydroxyurea derivative that prevents the conversion of arachidonic acid into leukotrienes by selectively blocking the 5-lipoxygenase enzyme.
Synonym: Abbott 64077; A 64077; 111406-87-2; Zyflo; Leutrol; 1-(1-(Benzo[b]thiophen-2-yl)ethyl)-1-hydroxyurea; Zyflo CR; Zileutonum; 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea; A-64077; N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea; ABBOTT-64077; A 64077; Zyflo (TN); Urea, N-(1-benzo[b]thien-2-ylethyl)-N-hydroxy-; MFCD00866097; (+-)-1-(1-Benzo(b)thien-2-ylethyl)-1-hydroxyurea; 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea; N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea; (+/-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea; (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea; Urea, N-(1-benzo(b)thien-2-ylethyl)-N-hydroxy-; (+/-)-1-(1-benzo(b)thien-2-ylethyl)-1-hydroxyurea; 1-(1-(1-benzothien-2-yl)ethyl)-1-hydroxyurea; N-(1-(benzo(b)thiophen-2-yl)ethyl)-N-hydroxyurea
CAS No.: 111406-87-2
Compound CID: 60490
Formula: C11H12N2O2S
Formula Weight: 236.29

Specification

Relative Density: 1.401 g/cm3
Stability: 3 years in powder form.
Storage: Storage at -20°C.
Applications: Zileuton is applied in respiratory research as an orally active 5-lipoxygenase inhibitor to study the blockage of leukotriene formation and its impact on airway inflammation.

Library Information

Target: Lipoxygenase; COX
Receptor: 5-Lipoxygenase; COX-1
Pathways: Apoptosis; Neuronal signaling; Metabolism; Immunology/Inflammation
Plate Number: AOCL-21
Plate Location: e2
Empty Location: a1-h1; a12-h12
Container: 96-well plate
Formulation: 10mM DMSO
DMSO Max Solubility: 75 mg/mL; 317.41 mM
ALogP: 2.184
HBA_Count: 1
HBD_Count: 1
Rotatable Bond: 2
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