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MeTC7
Cat. No.:
OB0626WX-3906
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
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Product Overview
Description:
MeTC7 is a small-molecule vitamin D receptor antagonist that actively downregulates receptor transactivation, suppresses intracellular transport proteins, and lowers immune checkpoint ligand levels in malignant cells. Beyond its concentration-dependent profile in restricting carcinoma cell viability and tumor growth, this lipophilic agent functions as a powerful targeting ligand when incorporated into lipid nanoparticles, selectively directing vehicle localization into pancreatic tissue architectures.
Synonyms:
2-bromo-acetic acid, (6S,8aR,8bR,10aR,11R,13aR)-11-[(1R)-1,5-dimethylhexyl]-2,3,5,6,7,8,8a,8b,10,10a,11,12,13,13a-tetradecahydro-2,8a,10a-trimethyl-1,3-dioxo-4a,13b-etheno-1H,9H-benzo[c]cyclopenta[h][1,2,4]triazolo[1,2-a]cinnolin-6-yl ester; (2S,4aR,4bR,6aR,7R,9aR)-4a,6a,12-Trimethyl-7-((R)-6-methylheptan-2-yl)-11,13-dioxo-2,3,4,4a,4b,5,6,6a,7,8,9,9a,12,13-tetradecahydro-1H,11H-9b,14a-ethenobenzo[c]cyclopenta[h][1,2,4]triazolo[1,2-a]cinnolin-2-yl 2-bromoacetate; [(2R,5R,6R,9R,10R,13S)-6,10,18-trimethyl-5-[(2R)-6-methylheptan-2-yl]-17,19-dioxo-16,18,20-triazahexacyclo[13.5.2.0¹,⁹.0²,⁶.0¹⁰,¹⁵.0¹⁶,²⁰]docos-21-en-13-yl] 2-bromoacetate; 1817841-22-7
CAS No.:
1817841-22-7
Compound CID:
165437232
Formula:
C32H48BrN3O4
Formula Weight:
618.7
Specification
Solubility in Ethanol:
1 mg/mL
Storage:
Storage at -20°C.
Applications:
MeTC7 serves as a synthetic small-molecule research compound for mechanistic and biochemical studies involving its reported molecular target. It supports structure–activity relationship investigations, target validation experiments, and characterization of target-associated signaling pathways in preclinical research.
