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31hP
Cat. No.:
OB0626WX-3667
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
31hP is a high-performance ionizable cationic lipid with an apparent pKa of 6.25, optimized for formulating lipid nanoparticles that co-deliver gene-editing elements or therapeutic transcripts. This ionizable core facilitates superior endosomal release and intracellular processing, driving potent target protein knockdown via Cas9/sgRNA platforms or eliciting high-efficiency serum antibody titers via antigen-encoding transcripts that exceed the performance of standard benchmark ionizable lipids.
Synonyms:
undecan-3-yl 4-(1-((2-(diethylamino)ethyl)(methyl)amino)-7-(heptadecan-9-yloxy)-7-oxohept-2-yn-1-yl)benzoate
Formula:
C49H86N2O4
Formula Weight:
767.2
Specification
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
31hP is used in lipid formulation research to investigate functional lipid components and their application in nanoparticle-based delivery systems. It supports studies of lipid composition, formulation optimization, and structure-related effects in lipid-based platforms.