Fludarabine (NSC 118218)

Cat. No.: OB0225WX-2421

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Fludarabine (NSC 118218) acts as a selective inhibitor of STAT1 activation, specifically depleting STAT1 protein and mRNA levels while also functioning as an inhibitor of DNA synthesis.

Synonym: FaraA, Fludarabinum, NSC 118218; 21679-14-1; F-Ara-A; 2-Fluoro Ara-A; (2R,3S,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 9-beta-D-Arabinofuranosyl-2-fluoroadenine; Fludarabina; Fludarabinum; Fluradosa; 9-b-d-arabinofuranosyl-2-fluoroadenine; 2-Fluoro-9-beta-D-arabinofuranosyladenine; (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-F-ARAA; 2-fluorovidarabine; MFCD00132942; (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-; Adenine, 9-beta-D-arabinofuranosyl-2-fluoro-; 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine; 2-Fluoroadenine arabinoside; (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9-purinyl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3S,4S,5R)-2-(6-amino-2-fluoro-purin-9-yl)-5-methylol-tetrahydrofuran-3,4-diol; (2R,3S,4S,5R)-2-(6-azanyl-2-fluoranyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-Fluoroadenine-9-beta-D-arabinofuranoside, DNA synthesis and methylation inhibitor

CAS No.: 21679-14-1

Compound CID: 657237

Formula: C₁₀H₁₂FN₅O₄

Formula Weight: 285.23

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Fludarabine (NSC 118218) is employed in hematology research as a purine nucleotide analog to investigate the disruption of DNA synthesis and the induction of apoptosis in lymphocytic leukemia cell lines.