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FLLL32
Cat. No.:
OB0125LY-081
Appearance:
Solid
Purity:
99.8%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
FLLL32 is an effective JAK2/STAT3 inhibitor and acts by binding to interferon-induced kinases such as JAKs, thereby inhibiting their activity.
Synonym:
1226895-15-3; (2E,2'E)-1,1'-(Cyclohexane-1,1-diyl)bis (3-(3,4-dimethoxyphenyl)prop-2-en-1-one); (E)-3-(3,4-dimethoxyphenyl)-1-[1-[ (E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]cyclohexyl]prop-2-en-1-one; (2E,2'E)-1,1'-Cyclohexylidenebis[3-(3,4-dimethoxyphenyl)-2-propen-1-one]
CAS No.:
1226895-15-3
Compound CID:
68019246
Formula:
C28H32O6
Formula Weight:
464.55
Specification
Targets & IC50:
JAK2: <5 μM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
FLLL32 can be used to study cell signaling, especially in tumor biology and immune regulation.
Library Information
Targets:
JAK; STAT; Apoptosis
Receptors:
Apoptosis; JAK; JAK2; STAT
Pathways:
Apoptosis; Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem cells
Plate Number:
AOCL-13
Plate Location:
e8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
85 mg/mL; 183 mM
Water Max Solubility:
1 mg/mL
Ethanol Max Solubility:
24 mg/mL; 51.7 mM
ALogP:
5.882
HBA_Count:
6
HBD_Count:
0
Rotatable Bond:
10
