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Orlistat
Cat. No.:
OB0225LY-0017
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
Orlistatis a lipase inhibitor that reduces dietary fat absorption by inhibiting pancreatic lipase and gastric lipase in the gastrointestinal tract.
Synonym:
Ro-18-0647; Tetrahydrolipstatin; 96829-58-2; (2S)-1-[(2S,3S)-3-Hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate; L-Leucine, N-formyl-, (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester; N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester; N-Formyl-L-leucine, ester with (3S,4S)-3-hexyl-4-((2S)-2-hydroxytridecyl)-2-oxetanone (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl N-formyl-L-leucinate; 2-Formamido-3-[(3-hexyl-4-oxo-oxetan-2-yl)methyl]-2-isobutyl-tetradecanoate
CAS No.:
96829-58-2
Compound CID:
3034010
Formula:
C29H53NO5
Formula Weight:
495.73
Specification
Relative Density:
0.976 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Orlistat can be used to treat obesity by reducing dietary fat absorption and promoting weight loss when combined with a low-fat diet and exercise.
Library Information
Targets:
Metabolic enzymes
Receptors:
FAS; Fatty acid synthase; Triacylglycerol lipase
Pathways:
Apoptosis; Metabolism
Plate Number:
AOCL-1
Plate Location:
b8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
45 mg/mL; 90.78 mM
Ethanol Max Solubility:
49.6 mg/mL; 100 mM
Solubility:
33% Ethanol + 67% PEG 400/PEG 300: 10 mg/mL
ALogP:
8.333
HBA_Count:
5
HBD_Count:
1
Rotatable Bond:
23
