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Bardoxolone methyl
Cat. No.:
OB0225LY-0283
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
Bardoxolone methyl is a promising anti-inflammatory and antioxidant agent.
Synonym:
RTA 402; CDDO Methyl ester; TP-155; NSC 713200; 218600-53-4; Methyl (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxylate; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; Methyl (4aS,6aR,6bS,12aS,14aR,14bR)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxylate; bardoxolone-methyl
CAS No.:
218600-53-4
Compound CID:
400769
Formula:
C32H43NO4
Formula Weight:
505.69
Specification
Relative Density:
1.15 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Bardoxolone methyl plays an important role in the study of chronic inflammatory mechanisms.
Library Information
Targets:
Nrf2 pathway; NF-kB pathway
Receptors:
IKK; Keap1-Nrf2
Pathways:
Apoptosis; Autophagy; Immunology/Inflammation; NF-κB
Plate Number:
AOCL-4
Plate Location:
f2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
18.33 mg/mL; 36.25 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
5.798
HBA_Count:
4
HBD_Count:
0
Rotatable Bond:
2
