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GSK2656157
Cat. No.:
OB0225LY-0426
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
GSK2656157 is a selective IRE1α inhibitor involved in the endogenous stress response.
Synonym:
1337532-29-2; GSK-2656157; 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone; 1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
CAS No.:
1337532-29-2
Compound CID:
53469059
Formula:
C23H21FN6O
Formula Weight:
416.45
Specification
Relative Density:
1.43 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
GSK2656157 can be used to study the relationship between endogenous stress and cell survival and cancer progression.
Library Information
Targets:
PERK
Pathways:
Apoptosis; Autophagy
Plate Number:
AOCL-6
Plate Location:
e2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
30 mg/mL; 72 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
2.926
HBA_Count:
4
HBD_Count:
1
Rotatable Bond:
3
