Rottlerin

Cat. No.: OB0225LY-0291

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Rottlerin is a compound from Mallotus philippinensis known to affect a variety of cellular physiological functions, especially apoptosis and autophagy.

Synonym: Mallotoxin; NSC 56346; NSC 94525; 82-08-6; (E)-1-(6-((3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl)-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-phenyl-2-propen-1-one; (E)-1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethylchromen-8-yl]-3-phenylprop-2-en-1-one; (E)-1-[6-[(3-Acetyl-2,4,6-trihydroxy-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one; 1-(6-(3-Acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one

CAS No.: 82-08-6

Compound CID: 5281847

Formula: C₃₀H₂₈O₈

Formula Weight: 516.54

Specification

Source: Mallotus philippinensis

Relative Density: 1.363 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Rottlerin can be used to study the mechanism of apoptosis or play an important role in the analysis of the role of autophagy.

Library Information

Targets: PKC family; CaMK family

Receptors: CaM kinase III; CKII; PKA; PKCα; PKCβ; PKCγ; PKCδ; PKCε; PKCζ; PKCη

Pathways: Apoptosis; Neuronal signaling; Chromatin/Epigenetic; Cytoskeletal signaling; Autophagy; Microbiology/Virology; Tyrosine kinase/adaptors; Proteases/Proteasome

Plate Number: AOCL-4

Plate Location: f11

Empty Location: a1-h1; a12-h12

Container: 96-well plate

Formulation: 10 mM DMSO

DMSO Max Solubility: 2 mg/mL; 3.87 mM