Tenovin-6

Cat. No.: OB0225WX-2611

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

Add to basket

Product Overview

Description: Tenovin-6 is a small molecule modulator that activates p53-mediated transcription while simultaneously inhibiting the enzymatic activity of SirT1, SirT2, and dihydroorotate dehydrogenase (DHODH).

Synonym: 1011557-82-6; 4-tert-Butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide; Benzamide, N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-; 4-(tert-butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide; 4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)phenylcarbamothioyl)benzamide; Tenovin 6; 4-~{tert}-butyl-~{N}-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide; 4-tert-butyl-N-[(4-{[5-(dimethylamino)pentanoyl]amino}phenyl)carbamothioyl]benzamide; N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-benzamide; MFCD11976906; N-(((4-((5-(Dimethylamino)-1-oxopentyl)amino)phenyl)amino)thioxomethyl)-4-(1,1-dimethylethyl)-benzamide; N-((4-(5-(dimethylamino)-(1-(oxopentyl)amino)phenyl)amino)thioxomethyl)-(4-(1,1-dimethylethyl)benzamide); N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4- (1,1-dimethylethyl)-benzamide

CAS No.: 1011557-82-6

Compound CID: 24772043

Formula: C₂₅H₃₄N₄O₂S

Formula Weight: 454.63

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Tenovin-6 is utilized in epigenetic and oncology research as a potent sirtuin inhibitor to investigate the activation of p53 signaling and the induction of apoptosis in various malignant cell lines.