Products
Online Inquiry
EHT 1864
Cat. No.:
OB0225LY-0043
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
EHT 1864 is a specific inhibitor of the Rac1 protein, a member of the Rho family of GTPases that plays a critical role in regulating actin cytoskeleton dynamics and cell motility.
Synonym:
EHT 1864 2HCl; 754240-09-0; 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride; 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride; 2-(Morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one dihydrochloride
CAS No.:
754240-09-0
Compound CID:
9938202
Formula:
C25H29Cl2F3N2O4S
Formula Weight:
581.47
Specification
Targets&IC50:
Rac2: 60 nM(Kd); Rac1b: 50 nM(Kd); Rac3: 250 nM(Kd); Rac1: 40 nM(Kd)
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
EHT 1864 can be used to inhibit Rac family GTPase.
Library Information
Targets:
Ras; Rho
Receptors:
Rac1; Rac1b; Rac2; Rac3
Pathways:
MAPK; Cell cycle/Checkpoint; GPCR/G protein
Plate Number:
AOCL-1
Plate Location:
e5
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
50 mg/mL; 85.99 mM
Water Max Solubility:
58.2 mg/mL; 100 mM
