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Norisoboldine
Cat. No.:
0225LY-0648
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
Norisoboldine is a potential therapeutic for rheumatoid arthritis that protects joints and regulates immune responses by suppressing macrophage activation and pro-inflammatory cytokine production through the down-regulation of MAPK signaling rather than NF-kappaB.
Synonym:
Laurelliptine; (+)-Laurelliptine; 23599-69-1; (+)-Norisoboldine; 4H-Dibenzo[de,g]quinoline-1,9-diol, 5,6,6a,7-tetrahydro-2,10-dimethoxy-, (6aS)-; (6aS)-2,10-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,9-diol; Norisoboldine, (+)-; (S)-(+)-Laurelliptine
CAS No.:
23599-69-1
Compound CID:
14539911
Formula:
C18H19NO4
Formula Weight:
313.35
Specification
Relative Density:
1.313 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Norisoboldine can be used in autoimmune research to explore its anti-arthritis effects and the regulation of T-cell differentiation.
Library Information
Target:
MAPK; Adenosine receptor
Receptor:
MAPK; Adenosine receptor
Pathways:
MAPK; GPCR/G protein signaling; Neuronal signaling
Plate Number:
AOCL-9
Plate Location:
d4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
250 mg/mL; 797.83 mM
Solubility:
Soluble in chloroform, dichloromethane, ethyl acetate, acetone, etc.
