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DSPE-Polysarcosine66
Cat. No.:
OB0626WX-3709
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR.
Size:
Add to basket
Product Overview
Description:
DSPE-Polysarcosine66 is an amine-functionalized, amphiphilic polymer conjugate consisting of a structural 1,2-distearoyl-rac-glycero-3-phosphoethanolamine lipid anchor coupled to an optimized polysarcosine block. Developed as a highly biocompatible, non-peptidic alternative to poly(ethylene glycol) shielding, this polymer architecture integrates into the lipid bilayer of self-assembled nanoparticles to modify surface characteristics and suppress immunogenic recognition during biological circulation.
Synonyms:
(2R)-3-((hydroxy(2-(2-(methyl((methylamino)methyl)amino)acetamido)ethoxy)phosphoryl)oxy)propane-1,2-diyl distearate; 1,2-Dioctadecanoyl-sn-glycero-3-Phosphoethanolamine-Polysarcosine66; 1,2-Distearoyl-sn-glycero-3-PE Polysarcosine66; 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-Polysarcosine66; 1,2-DSPE-Polysarcosine66; 18:0/18:0-PE-Polysarcosine66; DSPE-pSar66; PE(18:0/18:0)-Polysarcosine66
Formula:
(C3H5NO)nC43H87N2O8P
Formula Weight:
862.2
Specification
Solubility in Other Solvents:
Soluble in chloroform.
Storage:
Storage at -20°C.
Applications:
DSPE-Polysarcosine66 serves as a polymer-lipid conjugate reagent for lipid assembly and nanoparticle formulation studies. It supports research on polymer-modified lipid systems, surface stabilization strategies, and the influence of polysarcosine-lipid conjugates on lipid-based materials.
