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Cholesterol-PEG2000-Maleimide
Cat. No.:
OB0626WX-3581
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Cholesterol-PEG2000-Maleimide is a functionalized, PEGylated sterol derivative incorporating a terminal maleimide moiety engineered to undergo highly selective, covalent conjugation with free thiol groups via stable thioether linkages. This amphiphilic lipid conjugate acts as a robust molecular anchor within lipid bilayers and nanoemulsion matrices, facilitating the surface presentation of targeted peptide sequences to create specialized contrast or delivery vectors.
Conjugation:
Maleimide-conjugated
Synonyms:
(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (2-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)ethyl)carbamate
Formula:
(C2H4O)nC37H57N3O5
Specification
Solubility in DMSO:
≥10 mg/mL
Solubility in Ethanol:
≥10 mg/mL
Solubility in Other Solvents:
PBS: 1-10 mg/mL
Storage:
Storage at -20°C.
Applications:
Cholesterol-PEG2000-Maleimide serves as a functionalized lipid component for surface modification of lipid nanoparticles and liposomal systems. It supports conjugation-based functionalization strategies, development of ligand-modified lipid assemblies, and investigation of nanoparticle surface engineering approaches.