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BAMEA-O16B
Cat. No.:
OB0626WX-3900
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
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Product Overview
Description:
BAMEA-O16B is a redox-responsive ionizable cationic lipid incorporating a cleavage-sensitive disulfide bond within its hydrophobic tail core. This dynamic architecture co-assembles into lipid nanoparticles tailored for advanced genome editing, facilitating the synchronized intracellular delivery of Cas9 mRNA and single-guide RNA to achieve site-specific genomic knockdown and reduce circulating metabolic regulatory proteins.
Synonyms:
Bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-methyl-9-oxo-10-oxa-13,14-dithia-3,6-diazahexacosyl)azanediyl)dipropionate; 2490668-30-7
CAS No.:
2490668-30-7
Compound CID:
155374948
Formula:
C56H111N3O6S6
Formula Weight:
1114.9
Specification
Solubility in Ethanol:
Soluble in ethanol.
Storage:
Storage at -80°C.
Applications:
BAMEA-O16B serves as an experimental lipid reagent for lipid nanoparticle formulation and delivery research. It facilitates comparative assessment of lipid architectures, optimization of nanoparticle formulations, and investigation of lipid-mediated nucleic acid delivery performance.